Pulsetto science

The science of 
vagus nerve 

A natural, effective and scientifically proven way to decrease stress and anxiety, and to improve sleep.

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Pulsetto science vagus nerve

What is the vagus nerve?

  • The vagus nerve is your longest cranial nerve, connecting your brain to several of your internal organs.
  • It’s named after the Latin word for wandering. That’s because it starts at the brain before branching to almost every major organ in your body.
  • Your vagus nerve is responsible for signaling the brain to release calming neurotransmitters like acetylcholine and serotonin.
  • The vagus nerve is crucial for activating your relaxation response so you can “rest and digest.”
Pulsetto electrical impulses

What is vagus nerve stimulation?

Vagus nerve stimulation (or VNS), as it is commonly used today, works by delivering electrical impulses to the vagus nerve, which is the major highway between your brain and internal organs.

But now, using cutting-edge technology, we can stimulate the vagus nerve using non-invasive vagus nerve stimulation, nVNS. That means no need for invasive surgery or for needles!

Vagus nerve stimulation results

A study on cervical vagus nerve stimulation for stress reduction found that using VNS generated increased parasympathetic activity. After vNVS stimulation, the research observed a 64.5% increase in HRV (Heart Rate Variability), meaning a decrease in stress and anxiety for long-lasting relief.

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Pulsetto Stress reduction

Research about vagus nerve stimulation

Read the scientific research on stimulating the vagus nerve and what positive effects vagus nerve stimulators can have on the body.

Research proves that VNS reduces stress and combats PTSD. (Mouli et al., 2021)

Science has shown that VNS has a positive effect on heart rate variability (HRV), a factor in psychological well-being and quality of life. (Machetanz et al., 2021)

Studies show that VNS has a positive effect on mood and overall well-being. (Fersti et al., 2021)

Evidence indicates that vagus nerve stimulation (VNS) shows positive results in the prevention and treatment of stress-related psychiatric disorders. (Bremner et al., 2020)

Cervical Vagus Nerve Stimulation for Stress Reduction

How Pulsetto works

put on pulsetto

Put on Pulsetto

Using Pulsetto couldn't be simpler – select the mode in the app, put the vagus nerve stimulator around your neck, and let the vagus nerve stimulation begin.

Relax while Pulsetto works for you

Relax while Pulsetto works for you

Because the vagus nerve regulates vital functions, stimulating the vagus nerve with electric impulses relaxes the body, reducing stress and increasing heart rate variability.

Reap the benefits

Stimulating the vagus nerve with Pulsetto boosts your body’s relaxation response long-term, reducing stress and anxiety, and promoting better sleep.

Scientifically Proven To Make A Difference In Only 4 minutes

When your vagus nerve is ‘switched on’ by Pulsetto, it should only take a maximum of four minutes for you to feel more relaxed. In that time, your parasympathetic nervous system does its job, slowing your heart rate, turning off stress responses, and instilling calm across your entire body.

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Slowed heart rate

Your heart beating fast is a sign of stress. As it slows down, you’ll feel much calmer.

Pulsetto stomach icon
Better digestion

Do your guts ‘churn’ when you’re stressed? Stimulating your vagus nerve will help settle them.

Pulsetto Lower blood pressure icon
Slowed heart rate

Your heart beating fast is a sign of stress. As it slows down, you’ll feel much calmer.

Pulsetto Easier breathing icon
Easier breathing

Your parasympathetic nervous system helps you take a deep breath and relax.

Ready to feel inner peace?

When using Pulsetto, users reports a boost in well being.*

Stress less


Reported less anxiety

Sleep better


Expressed higher quality sleep

Feel happier


Improve mental health

*Based on a Vagus stimulation studies

Pulsetto 4 min

What are you waiting for?

Pulsetto is the easiest, quickest way to deal with stress and anxiety.

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Want to know more? Email us any time! Please reach out to info@pulsetto.tech and we’ll be in touch.

What does vagus nerve stimulation do?

Vagus nerve stimulation (or VNS) works by delivering electrical impulses to the vagus nerve, which is the major highway between the brain and internal organs. Surgically inserted implants have been used to stimulate the vagus nerve for treating epilepsy and depression for over 30 years. A similar effect is achieved from acupuncture, where the vagus nerve is stimulated with needles.

The Pulsetto device uses specific electric impulses to stimulate the vagus nerve – this is known as non-invasive vagus nerve stimulation (nVNS). The Pulsetto vagus nerve stimulation increases heart-rate variability (HRV), which connects to a more relaxed state, reduced stress, and the ability to sleep better.

Is vagus nerve stimulation safe?

The Pulsetto device is FCC certified. This means that Pulsetto is approved for well-being use and compliant with the strict laws of the Federal Communication Commission.

The FCC certification ensures that:

  • Pulsetto is based on scientific evidence.
  • Pulsetto is safe to use.


What is non-invasive vagus nerve stimulation?

Non-invasive vagus nerve stimulation (nVNS) is a way to stimulate the vagus nerve with electric impulses from outside of the body without the need for invasive surgery. 

Pulsetto technology uses the Bluetooth ultra low radio frequency energy (ULRE) – which safely passes into the body.

What is vagus nerve stimulation used for?

Vagus nerve stimulation has been used in treating epilepsy patients and people with depression. Due to its effects on the vagus nerve and body as a whole, it can also be used to achieve a more relaxed state, reduce stress and anxiety, and achieve better sleep.

What does vagus nerve stimulation feel like?

Vagus nerve stimulation with Pulsetto feels like a pleasant, light vibration or a tingling sensation in your neck area where the device sits.