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Vagus Nerve Stimulation for Long COVID | Do HRV Exercises & Non-Invasive Treatment Work?

Vagus Nerve Stimulation for Long COVID | Do HRV Exercises & Non-Invasive Treatment Work?

Key Takeaways

  • Vagus nerve stimulation (VNS) may be a promising method for managing long COVID symptoms.
  • VNS activates the parasympathetic nervous system and reduces inflammation.
  • HRV (Heart Rate Variability) exercises like deep breathing and cold showers can complement VNS.
  • Non-invasive VNS devices like Pulsetto are an accessible and user-friendly way to stimulate the vagus nerve.
  • Using Pulsetto regularly can relieve stress, anxiety, and insomnia, contributing to the better management of long COVID.

Vagus Nerve Stimulation and Long COVID

Long COVID is a term used to describe the lingering symptoms that some individuals experience after they recover from the initial COVID-19 infection. These symptoms can include chronic fatigue, brain fog, headaches, and irregular blood pressure. The condition can significantly impact your quality of life.

How Vagus Nerve Stimulation Works

The vagus nerve is a critical part of our body's parasympathetic nervous system that regulates several essential functions, including heart rate, digestion, and immune response. By stimulating the vagus nerve, we activate the parasympathetic nervous system, which reduces inflammation and promotes a state of calm.

Vagus nerve stimulation (VNS) involves sending mild electrical impulses to the vagus nerve by various methods. This stimulation can improve your mood, reduce anxiety, and enhance your sense of well-being. For individuals with long COVID, VNS may be beneficial in addressing the neurological symptoms associated with the condition.

Benefits for Long COVID Patients

Patients with long COVID often struggle with debilitating symptoms that may persist for months. Vagus nerve stimulation offers several potential benefits including:

  • Reduced Fatigue: VNS can help alleviate chronic fatigue, one of the most common symptoms of long COVID.
  • Improved Cognitive Function: By reducing brain fog and enhancing mental clarity, VNS can help individuals regain their cognitive abilities.
  • Better Mood and Reduced Anxiety: VNS can promote a sense of calm, helping individuals manage their anxiety levels and improve their mood.

Regulated Blood Pressure: VNS can help stabilize blood pressure, reducing the risk of complications associated with long COVID.

Clinical Evidence and Studies

Several studies have tested the effectiveness of vagus nerve stimulation in managing long COVID symptoms. Early small-scale trials have shown promising results, with participants reporting reductions in chronic fatigue, headaches, and irregular blood pressure.

For example, a pilot study published in Frontiers in Neurology performed on 24 female participants found significant improvements in cognitive function, anxiety, depression, and sleep after a 10-day t-VNS intervention (30 min/session, twice a day). 

A 2022 clinical trial designed for at-home use of t-VNS demonstrated that participants could safely and effectively self-administer the treatment. This trial suggested that t-VNS might lead to mild to moderate improvements in mental fatigue and other long COVID symptoms although the study was not large enough to draw definitive conclusions about efficacy.

These findings suggest that VNS could be a valuable tool in treating long COVID.

Pulsetto: Revolutionary Vagus Nerve Stimulator


Reduce stress and anxiety in just 4 minutes with Pulsetto, the innovative vagus nerve stimulator designed to biohack your parasympathetic nervous system. Clinically proven and FCC-certified, Pulsetto has helped 86% of users feel calmer and less anxious within two weeks. The device is rated 4.5/5 by over 20,137 customers. Enjoy benefits like free worldwide shipping, a 30-day money-back guarantee, a 2-year warranty, and recyclable materials. 


Experience the calming effect of Pulsetto today!

Using HRV Exercises for Long COVID

Heart Rate Variability (HRV) exercises are another effective way to manage long COVID symptoms. HRV refers to the time variation between each heartbeat, and a higher HRV score is associated with better health and resilience.

HRV exercises can help reduce stress, improve mood regulation, and enhance well-being. For example, deep breathing exercises can help calm the nervous system and reduce anxiety. Mindfulness meditation can help individuals stay present and focused, reducing the mental fog often associated with long COVID.

Examples of Effective HRV Exercises

Here are some effective HRV exercises that can be easily incorporated into your daily routine:

  • Deep Breathing: Sit comfortably and take a slow, deep breath in through your nose, allowing your abdomen to expand. Hold your breath for a few seconds, then slowly exhale through your mouth. Repeat this process for 5-10 minutes.
  • Mindfulness Meditation: Find a quiet space and sit comfortably. Close your eyes and focus on your breath, letting go of any distracting thoughts. Practice this for 10-15 minutes daily.
  • Cold Showers: Start with a warm shower and gradually lower the temperature until the water is cold. Stay under the cold water for 1-2 minutes, focusing on deep, steady breathing.

Cold showers can invigorate the body and improve circulation. 

Non-Invasive Vagus Nerve Stimulation Devices for Long COVID Treatment

Non-invasive vagus nerve stimulation devices are a convenient and effective way to manage long COVID symptoms. These devices are designed to stimulate the vagus nerve without surgical implantation, making them accessible to a broader range of individuals.

Overview of Non-Invasive Devices

Non-invasive VNS devices typically use electrodes placed on the skin to deliver mild electrical impulses to the vagus nerve. These devices are user-friendly, can be used at home, and are a practical solution for those looking to manage their long COVID symptoms.

Benefits Over Traditional Methods

Non-invasive VNS devices offer several advantages over traditional implantable devices:

  • Accessibility: Anyone can use non-invasive VNS devices. 
  • Convenience: These devices are suitable for home use and make it easier to incorporate VNS into a daily routine.
  • Cost-Effectiveness: Non-invasive devices are generally more affordable than implantable devices, making them a cost-effective option for many individuals.

How to Use Non-Invasive Devices

Most non-invasive VNS devices come with clear instructions on electrode placement and settings for optimal vagus nerve stimulation. Follow manufacturer guidelines for safe and effective use.

Here are some general steps to follow when using a non-invasive VNS device:

  • Clean the area where the electrodes will be placed to ensure good contact.
  • Apply the conducting gel. 
  • Attach the electrodes according to manufacturer instructions.
  • Turn on the device and adjust the settings to a comfortable level.
  • Use the device for the recommended duration, typically 15-30 minutes per session.

Popular Non-Invasive Devices on the Market

Several non-invasive VNS devices are available on the market, each with unique features and benefits. One such device is Pulsetto, which has gained popularity for its effectiveness and user-friendly design.

Other popular non-invasive VNS devices include:

  • gammaCore: A handheld device that delivers mild electrical impulses to the vagus nerve through the skin.
  • Nurosym: A wearable device designed to stimulate the vagus nerve and improve HRV.

Pulsetto Vagus Nerve Stimulation

What is Pulsetto?

Pulsetto is a non-invasive VNS device designed to stimulate the vagus nerve non-invasively and provide quick stress relief and relaxation. It offers quick results, typically taking effect in as little as 4 minutes, and is highly praised for its adjustable settings, allowing users to tailor their relaxation experience. 

A person holding a Pulsetto device.

How Pulsetto Works

Pulsetto works by delivering mild electrical impulses to the vagus nerve through electrodes placed on the skin. These impulses help activate the parasympathetic nervous system, promoting relaxation and reducing stress.

Choose from different intensities and programs (e.g., stress, anxiety, sleep, burnout, pain management) to personalize your experience.

Effectiveness for Long COVID

Since VNS has shown promise in helping individuals manage long COVID symptoms, Pulsetto might come in handy for people living with symptoms of long COVID. By stimulating the vagus nerve, it can help reduce chronic fatigue, improve cognitive function, and enhance overall well-being.

While individual experiences may vary, Pulsetto is a convenient and effective way to manage long COVID symptoms without invasive procedures. Quick results and customizable settings make it a valuable addition to any wellness routine.

The many health benefits of Pulsetto.

Usage Instructions

Using Pulsetto is straightforward and designed to fit seamlessly into your daily routine. Here are the steps to get started:

  1. Turn on the device by pressing the button, then sync it with the app to get started.
  2. Ensure the skin where you place the electrodes is clean and dry. 
  3. Apply gel on the neck or on the electrodes for better contact.
  4. Attach the electrodes as per the device's instructions. They must be placed on the neck—where the vagus nerve is accessible.
  5. Turn on Pulsetto, open the app, choose a mode for stress, anxiety, sleep, burnout, or pain management, and enjoy the calming effects.
  6. Use the device for the recommended duration, usually around 6-10 minutes per session. Remember that you should use it for fewer minutes when using the device for the first few times. 
  7. Sit or lie down in a comfortable position while using the device. Focus on deep breathing to enhance the relaxation experience.

A person pressing the buttons on their Pulsetto device.

Experience the calming effect of Pulsetto today!

Frequently Asked Questions (FAQ)

What is the Vagus Nerve?

The vagus nerve is one of the longest nerves in the body, running from the brainstem to the abdomen. It plays a crucial role in the parasympathetic nervous system, helping to regulate vital functions such as heart rate, digestion, and immune response. By stimulating the vagus nerve, we can activate the body's natural relaxation and healing processes.

Can Vagus Nerve Stimulation Cure Long COVID?

While vagus nerve stimulation is not a cure for long COVID, it can help manage and alleviate some of the symptoms associated with the condition. VNS can reduce chronic fatigue, improve cognitive function, and enhance overall well-being, making it a valuable tool in the management of long COVID.

How Long Does it Take to See Results?

The time it takes to see results from vagus nerve stimulation can vary from person to person. Some individuals may notice improvements within a few sessions, while others may require more extended use to experience significant benefits. Consistency is key, so it's essential to use the device regularly as part of your wellness routine.

Are There Any Side Effects?

Most users of non-invasive vagus nerve stimulation devices like Pulsetto experience minimal side effects. Some individuals may experience mild discomfort or tingling at the site of electrode placement. Follow the manufacturer's instructions and start with a lower intensity to minimize potential side effects.

If you experience any adverse effects or have concerns about using the device, consult a healthcare professional for guidance.

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Pulsetto does not provide medical advice, diagnosis or treatment.

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