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Vagus Nerve Stimulation for Heart Rate Regulation: Do HRV Exercises and Non-Invasive Treatments Work?

Vagus Nerve Stimulation for Heart Rate Regulation: Do HRV Exercises and Non-Invasive Treatments Work?

Every heartbeat is the result of a quiet negotiation inside your nervous system. One side speeds the heart up. The other slows it down. The slowing-down side runs almost entirely through a single nerve: the vagus nerve, the main highway of your parasympathetic, or "rest and digest," branch. When people search for vagus nerve stimulation for heart rate regulation, what they usually want to know is whether they can influence that negotiation on purpose, and whether tools like paced breathing or a non-invasive vagus nerve stimulation device can nudge the balance toward calm.

This guide walks through the physiology in plain language: how the vagus nerve acts as the parasympathetic brake on the heart, what heart rate variability (HRV) actually measures, why HRV is one of the clearest windows into autonomic balance, and what the research says about two practical approaches to supporting it: "HRV exercises" (slow breathing and HRV biofeedback) and non-invasive vagus nerve stimulation (nVNS). Pulsetto is a general wellness product and is not intended to diagnose, treat, cure, or prevent any disease or medical condition. Nothing here is medical advice. If you have a cardiovascular condition, a cardiac arrhythmia, a pacemaker, or any other implanted electrical device, talk with a healthcare provider before trying vagus nerve stimulation of any kind.

Heart rate versus heart rate variability: two different numbers

It helps to separate two measurements that sound similar but mean different things.

Heart rate is how many times your heart beats per minute. A typical resting heart rate for adults sits somewhere in the range of 60 to 100 beats per minute, with trained or relaxed individuals often lower. It is a single average over a window of time.

Heart rate variability (HRV) is the beat-to-beat variation in the time between heartbeats. Even when your heart rate reads a steady 60 beats per minute, the actual gaps between beats are not identical. One interval might be 0.92 seconds, the next 1.04, the next 0.98. HRV quantifies that fluctuation.

Counterintuitively, more variation is generally the healthier sign. A heart that can vary its rhythm moment to moment is a heart receiving rich, responsive input from the parasympathetic nervous system. A flatter, more metronomic rhythm often reflects a nervous system stuck in sympathetic ("fight or flight") dominance. This is why HRV is treated as the clearest non-invasive marker of vagal tone and autonomic balance. If you want the deeper version of this, the explainer on why heart rate variability matters breaks down the science and the practical reasons to track it.

In a comprehensive review of HRV metrics and norms, Shaffer and Ginsberg lay out why the measure has become so widely used: it is non-invasive, it tracks autonomic activity in real time, and it correlates with how well the body adapts to demand and recovers from stress [1]. Crucially, HRV is sensitive to stress. A meta-analysis by Kim and colleagues, pooling data across studies, found that psychological stress is reliably associated with reduced HRV, especially in vagally mediated indices [2]. In other words, when life loads up, the variability tends to shrink. That makes HRV a useful, trackable signal of where your autonomic balance sits.

Vagus Nerve Stimulation for Heart Rate Regulation: Do HRV Exercises and Non-Invasive Treatments Work?

The vagus nerve as the parasympathetic brake on your heart

To understand vagus nerve stimulation for heart rate regulation, you have to understand the wiring.

Your heart has its own pacemaker, the sinoatrial (SA) node, which sets a baseline rhythm. But the SA node does not work in isolation. It receives constant input from the autonomic nervous system through two opposing channels:

  • The sympathetic branch releases noradrenaline, which speeds the heart up and increases the force of each contraction. This is the accelerator.

  • The parasympathetic branch, carried almost entirely by the vagus nerve, releases acetylcholine onto the SA node, which slows the heart down. This is the brake.

The vagus nerve is the longest cranial nerve in the body, wandering from the brainstem down through the neck and into the chest and abdomen (its name comes from the Latin for "wandering"). Along the way it innervates the heart. When vagal activity rises, acetylcholine slows the firing of the SA node and the heart rate drops. When vagal activity falls, the brake eases off and the rate climbs. If you want the full tour of the nerve's pathways and roles, the guide to vagus nerve anatomy and core functions maps it out.

This braking action is fast and continuous. Every breath you take subtly modulates it: heart rate tends to rise slightly on the inhale and fall on the exhale, a phenomenon called respiratory sinus arrhythmia. That breathing-linked rhythm is itself a large part of what HRV captures, and it is one reason breathing exercises can shift the numbers.

Vagal influence on the heart is well documented in controlled stimulation research. Gurel and colleagues quantified the acute physiological effects of transcutaneous cervical (neck) vagus nerve stimulation in people under psychological stress, and observed measurable shifts in cardiovascular and autonomic biomarkers consistent with increased parasympathetic engagement and a dampened sympathetic stress response [3]. In a separate double-blind, randomized, sham-controlled trial, the same group found that transcutaneous cervical VNS reduced sympathetic responses to stress [4]. The vagal brake, in short, is not just a textbook concept. It can be engaged.

A practical note before going further: when the question is "does the vagus nerve decrease heart rate?", the answer is yes, that is precisely its role on the heart. But influencing heart rate as a downstream consequence of supporting vagal tone for general wellness is very different from using any device to manage a cardiac condition. We will keep that line clearly drawn throughout.

Try Pulsetto. Pulsetto is a hands-free, CE and FCC certified vagus nerve stimulation wearable for the neck, designed to support relaxation, HRV, and a calmer baseline in around four minutes a day. It is a general wellness device, not a medical treatment. Meet Pulsetto to see how it fits a daily routine.

What is a "good" HRV?

This is one of the most common follow-up questions, and the honest answer is: it depends, and the most useful comparison is against yourself.

HRV is shaped by age, sex, fitness, genetics, sleep, alcohol, illness, and stress. It declines naturally with age, and it varies widely between individuals. A value that is perfectly healthy for one 55-year-old might look low next to a fit 25-year-old. Because of that spread, fixating on whether your number is "good" relative to other people is less useful than watching your own trend over weeks and months.

That said, population norms exist, and Shaffer and Ginsberg's review compiles reference ranges across the common time-domain and frequency-domain metrics (such as RMSSD and high-frequency power), which is part of why it is cited so often [1]. If you want age- and sex-adjusted context for where a reading sits, the HRV chart by age and gender lays out typical ranges and how to interpret your own score sensibly.

The practical takeaway: a "good" HRV is one that is stable or trending upward for you, recovers after stress and poor sleep, and reflects a nervous system that can shift flexibly between activation and rest. That flexibility, not a single magic number, is the goal.

Do HRV exercises work? Slow breathing and HRV biofeedback

"HRV exercises" is a loose label, but it usually points at two related practices: slow, paced breathing and HRV biofeedback. Both aim to engage the vagal brake deliberately, and both have a real evidence base.

Slow, paced breathing

Breathing is the most direct lever most people have over their autonomic nervous system. Because heart rate naturally falls on the exhale, lengthening and slowing the exhale amplifies parasympathetic (vagal) activity. Slow breathing at around five to six breaths per minute tends to maximize respiratory sinus arrhythmia and, with it, the variability HRV measures.

A meta-analysis of randomized controlled trials by Fincham and colleagues found that breathwork was associated with meaningful reductions in self-reported stress compared with control conditions [5]. Jensen and colleagues looked specifically at the mechanism, comparing deep breathing exercises and transcutaneous auricular vagus nerve stimulation, and observed that paced deep breathing modulated HRV, reinforcing the link between slow breathing and vagally mediated heart rate variability [6]. The appeal of slow breathing is obvious: it is free, portable, and has essentially no downside for a healthy person.

HRV biofeedback

HRV biofeedback takes paced breathing a step further. Using a sensor and a screen, you breathe at your personal "resonance frequency" (often near six breaths per minute) while watching your HRV respond in real time, training the system over repeated sessions.

The evidence here is among the strongest in the whole space. A systematic review and meta-analysis by Lehrer and colleagues concluded that HRV biofeedback improves outcomes across emotional, physical, and performance domains, with effects on stress and anxiety standing out [7]. A separate meta-analysis by Goessl and colleagues, focused specifically on stress and anxiety, found that HRV biofeedback training produced a large reduction in self-reported stress and anxiety [8]. Taken together, the message is consistent: deliberately training your breathing in a way that engages the vagal brake can measurably shift how stressed you feel, and it does so through the same parasympathetic pathway that governs heart rate.

So, do HRV exercises work? For supporting autonomic balance and reducing perceived stress in general wellness contexts, the research is encouraging. They are a sensible first thing to try, and they pair naturally with the breathing approaches built into many vagus nerve stimulation routines.

Can non-invasive vagus nerve stimulation raise HRV?

This is the crux for anyone considering a device. Non-invasive vagus nerve stimulation (nVNS) means stimulating the vagus nerve from outside the body, with no surgery and no implant. There are two common access points to the same nerve:

  • Auricular (ear): the vagus nerve has a branch that surfaces at part of the outer ear, so transcutaneous auricular VNS (taVNS) reaches it through the ear.

  • Cervical (neck): the main vagal trunk runs through the neck, so transcutaneous cervical VNS reaches it there. This is where Pulsetto sits.

Both target the same nerve through different doors. The deeper distinction, and how external stimulation differs from surgical implants, is covered in non-invasive vagus nerve stimulation explained.

The research on whether nVNS can raise HRV markers is genuinely promising, and it is also genuinely nuanced. Both deserve to be stated plainly.

On the encouraging side: Geng and colleagues studied taVNS in healthy young people and reported changes in HRV consistent with increased parasympathetic activity [9]. Forte and colleagues, in a study pointedly titled "Ear your heart," likewise observed effects of auricular stimulation on heart rate variability in healthy participants [10]. Sanchez-Perez and colleagues found that auricular VNS reduced acute stress in young healthy adults [11]. And a more recent study using transcutaneous cervical stimulation reported clear signs of enhanced parasympathetic activity, with time-domain HRV indices improving during stimulation.

On the honest-nuance side: the acute effects do not show up identically in every study or every protocol. A living, interactive Bayesian meta-analysis by Wolf and colleagues weighed the accumulated evidence on whether taVNS affects vagally mediated HRV and concluded that the acute effect, while present in the data, is variable and sensitive to factors like stimulation parameters and study design [12]. A systematic review by Soltani and colleagues on baroreflex sensitivity and HRV in healthy subjects reached a similarly measured conclusion: effects are observed, but heterogeneity across protocols is real [13]. Age also appears to matter; Gianlorenco and colleagues found that age modifies how taVNS affects HRV in healthy subjects [14]. And a critical review by Yap and colleagues catalogued exactly these translation challenges, from dosing to outcome measurement, that the field is still working through [15].

The fair synthesis is this. The mechanism is sound and well established (the vagus nerve is the parasympathetic brake on the heart). Multiple studies show nVNS can raise HRV markers and reduce stress reactivity. But the size of the acute effect varies, and the most consistent gains tend to show up with regular, repeated use rather than from a single session. That last point matters for how anyone should set expectations: treat nVNS as a practice that builds over weeks, not a switch.

Does Pulsetto increase HRV?

Here is the direct, honest answer. Pulsetto is a non-invasive cervical vagus nerve stimulation device designed to support HRV and autonomic balance, and it tracks HRV in its companion app so you can watch your own trend. The broader nVNS research summarized above suggests that stimulating the vagus nerve can raise HRV markers, with effects that tend to build with consistent use. Pulsetto is built around that same parasympathetic pathway, applying gentle electrical stimulation to the vagus nerve at the neck for short daily sessions.

What Pulsetto does not do is claim to treat, regulate, or manage any cardiac condition, blood pressure, or heart rate as a medical outcome. It is a general wellness device. The accurate framing is "designed to help support HRV, vagal tone, and a calmer baseline," and the most reliable way to see whether it helps you is to use it consistently and watch your own HRV and how you feel over time.

On the question of what the company's own data shows: in Pulsetto's own randomized open-label pilot study (n=40, 4 weeks), participants reported a 55.9% reduction in depressive symptoms (PHQ-9), a 45.3% reduction in anxiety symptoms (GAD-7), and a 41.0% improvement in sleep quality (PSQI). Bilateral stimulation reduced the chronic-stress biomarker hair cortisol by 47.5%, compared with 31.4% for unilateral stimulation. Those are stress, mood, sleep, and cortisol outcomes, attributed to that specific pilot, and they speak to the autonomic and stress-regulation side of the picture rather than to any cardiac claim. You can read more on the methodology and the wider literature on the Pulsetto science page.

A reasonable way to think about it: nVNS engages the same vagal pathway that slow breathing and biofeedback engage, just through electrical stimulation instead of breath. For people who find it hard to sit and breathe their way to calm, a hands-free device that runs in around four minutes can be an easier on-ramp to the same parasympathetic territory.

Try Pulsetto. A four-minute, hands-free session you can do while reading or winding down for bed, plus a free app that tracks HRV and sleep with no subscription required for core use. Explore the Pulsetto FIT model or compare the lineup to find the right fit.

What about blood pressure and other cardiovascular markers?

People often arrive at this topic asking whether vagus nerve stimulation lowers blood pressure. This needs care, so the answer is deliberately conservative.

Vagal activity is part of the body's broader cardiovascular regulation in research settings; the baroreflex (the loop that adjusts heart rate and vessel tone in response to blood pressure changes) is partly vagally mediated, and Soltani and colleagues reviewed how auricular stimulation interacts with baroreflex sensitivity and HRV in healthy subjects [13]. That is a statement about physiology and research, hedged and attributed.

It is not a claim that Pulsetto, or non-invasive vagus nerve stimulation generally, lowers blood pressure or should be used to manage blood pressure, a cardiac arrhythmia, or any cardiovascular condition. It does not, and it should not. If you are managing blood pressure or any heart condition, that belongs with your healthcare provider, and you should speak with them before adding any vagus nerve stimulation device to your routine. Pulsetto's role is general wellness: supporting HRV, vagal tone, and stress resilience, not treating disease.

HRV exercises you can do at home

You do not need any equipment to start engaging the vagal brake. These breathing patterns are the core "HRV exercises," and they pair well with a device-based routine for anyone who uses one. If you are interested in the wider toolkit, the guide on how to activate the parasympathetic nervous system goes broader than breath alone.

Resonance (coherent) breathing. Breathe at a slow, even pace of about five to six breaths per minute: roughly a 5-second inhale and a 5- to 6-second exhale. This rate tends to maximize respiratory sinus arrhythmia and the HRV that comes with it. Aim for 5 to 10 minutes.

Extended-exhale breathing. Make the exhale longer than the inhale, for example inhale for 4 seconds and exhale for 6 to 8. Because the heart slows on the exhale, lengthening it leans into parasympathetic activation. This is one of the simplest ways to feel a shift quickly.

Box breathing. Inhale for 4, hold for 4, exhale for 4, hold for 4. The structure makes it easy to keep pace and is a useful reset during a tense moment.

Physiological sigh. Take a normal inhale, add a second short top-up inhale, then a long, slow exhale. Repeated a few times, this pattern is a fast way to down-regulate after a spike of stress.

Consistency beats intensity. A few minutes daily does more than an occasional long session, and the same is true of device-based nVNS routines: the gains tend to compound with regular use. Many people stack the two, doing a short breathing practice alongside a vagus nerve stimulation session, since both work the same pathway. For a structured starting point, the Pulsetto quick start guide covers sensible cadence and session timing.

Non-invasive vagus nerve stimulation devices: how the category compares

If you are weighing a device, it helps to see how the main consumer options differ in placement, format, and what they are a good fit for. Placement (neck versus ear versus elsewhere), whether it is hands-free, session length, and whether tracking is built in are the practical differences that matter day to day. The table below is an overview; a fuller breakdown lives in the roundup of the best vagus nerve stimulation devices.

Device

Stimulation type

Placement

Hands-free

Typical session

Approx. price

Pulsetto

Electrical nVNS (bilateral)

Neck (cervical)

Yes

Around 4 min

Around $269 (Lite) / $296 (FIT)

Neuvana Xen

Electrical taVNS, synced to music

Ear (auricular)

No (earbuds)

10-30 min

Around $399-449

Nurosym

Electrical taVNS

Single ear clip

No

About 30 min

Around €699

Vagustim

Electrical taVNS (both ears)

Ear (auricular)

No

App-guided

Around $390

Amofit S

Non-contact electromagnetic

Chest

Yes

Varies

Around $248

Sensate

Infrasonic vibration

Chest

Yes

10 min

Around $300

Apollo Neuro

Haptic vibration

Wrist/ankle

Yes

Varies

Around $349

Truvaga

Electrical, handheld

Neck (cervical)

No (handheld)

2 min

Around $199-499


Prices are approximate and change over time. A few honest distinctions worth keeping in mind:

Pulsetto is the device we know best and the one designed end to end around HRV support. It delivers direct electrical stimulation to the vagus nerve at the neck, bilaterally, and it is hands-free, so you can wear it while reading or settling into bed rather than holding anything in place. Sessions run around four minutes. The free lifetime app includes Stress, Sleep, Burnout, Pain, and Anxiety programs plus HRV and sleep tracking and guided breathing, with no subscription required for core use (a Premium tier is optional). It is CE and FCC certified, made in Lithuania in the EU, and backed by its own randomized open-label pilot study alongside the wider peer-reviewed nVNS literature. Two models are available, Pulsetto Lite and Pulsetto FIT; the Pulsetto FIT versus Pulsetto Lite comparison covers which suits whom. One clarification that often comes up: Pulsetto is not a TENS unit. TENS targets muscles and pain signals; Pulsetto targets the vagus nerve and autonomic balance.

Neuvana Xen is an earbud-style auricular device synced to music, a good fit for people who want to combine ear stimulation with music listening. It needs the app and audio to work as designed, and sessions tend to run longer than a few minutes.

Nurosym is a single-ear clip with a controller and has the deepest external published clinical evidence base of the consumer options, a good fit for buyers who prioritize the strongest research at a premium price (around €699). Sessions are about 30 minutes and it is held at the ear.

Vagustim uses both-ear earpieces with an app, a good fit for a lower-cost app-controlled ear device. It is newer with fewer reviews, and some users report mild ear discomfort.

Amofit S is a non-contact electromagnetic unit worn on the chest, a good fit for an inexpensive contactless option, with less independent evidence behind it.

Sensate rests on the chest and uses infrasonic vibration rather than electrical stimulation, a good fit for a meditation-style relaxation ritual in roughly 10-minute lie-down sessions.

Apollo Neuro is a wrist or ankle wearable using haptic vibration, not electrical vagus stimulation, a good fit for a discreet wearable, though it works through a different mechanism than the electrical devices here.

Truvaga is a handheld cervical device with mainly US availability and short held sessions, a good fit for handheld cervical use, mainly in the US. Hoolest VeRelief is another handheld cervical option held in place. The prescription cervical option, gammaCore Sapphire, is obtained through a clinician rather than bought directly.

For specific use cases, there are focused guides on the best HRV device and the best nervous system regulation device to narrow the field further.

How to choose a device for HRV support

A few questions usually settle the decision:

Where do you want it placed? Neck (cervical) devices like Pulsetto reach the main vagal trunk and tend to be quicker; ear (auricular) devices reach a vagal branch and often run longer sessions. Both are valid; the choice is partly about comfort and routine.

Hands-free or held? If you want to read, work, or fall asleep during a session, a hands-free wearable is far easier to keep up than a handheld unit you have to hold against your neck.

Does it track HRV? A device that logs HRV and sleep lets you actually watch your own trend, which is the whole point given how individual HRV is. Pulsetto builds tracking into its free app.

Subscription or not? Some apps lock core features behind a paywall. Pulsetto's core programs work without a subscription, with Premium optional; the note on whether you need Premium spells out the split.

Evidence and certification. Look for general wellness certification (CE, FCC) and a transparent stance on the research. The broader vagus nerve stimulation ultimate guide is a good place to ground expectations before buying.

Safety, contraindications, and who should not use vagus nerve stimulation

Non-invasive vagus nerve stimulation is generally well tolerated as a general wellness practice, but it is not for everyone, and the cardiac contraindications in particular deserve emphasis. Consult a healthcare provider before use, especially if you have any cardiovascular condition. Do not use a vagus nerve stimulation device if any of the following apply to you:

  • Pacemaker

  • Any implanted electrical medical device

  • Epilepsy or a seizure disorder

  • Pregnancy

  • Cardiac arrhythmia or a serious cardiovascular condition (consult a doctor first)

  • Recent neck or throat surgery (consult a doctor first)

  • Carotid artery conditions

Because the vagus nerve directly influences heart rhythm, anyone with an arrhythmia, a pacemaker, or another cardiac concern should treat clearance from a clinician as non-negotiable. The detailed contraindications of using Pulsetto go further, and the page on what effects to expect from vagus nerve stimulation sets sensible expectations for a first few weeks.

Frequently asked questions

Does Pulsetto increase HRV?

Pulsetto is a non-invasive cervical vagus nerve stimulation device designed to support HRV and autonomic balance, and it tracks HRV in its app so you can follow your own trend. Research on nVNS suggests that stimulating the vagus nerve can raise HRV markers, with effects that tend to build with consistent use rather than from a single session. Pulsetto is a general wellness device, not a medical treatment, and the most reliable way to see whether it helps you is to use it regularly and watch your own HRV over time.

How does the vagus nerve control heart rate?

The vagus nerve is the main parasympathetic pathway to the heart. It releases acetylcholine onto the sinoatrial node, the heart's natural pacemaker, which slows the firing rate and lowers heart rate. When vagal activity rises, the heart slows; when it falls, the heart speeds up. The vagus nerve is the brake, and the sympathetic nervous system is the accelerator, with the two constantly balancing each other.

Does the vagus nerve decrease heart rate?

Yes. On the heart, the vagus nerve's role is to slow the rate by acting on the sinoatrial node. This is why slow breathing, which boosts vagal activity on the exhale, tends to calm the heart, and why vagal activity is closely tied to the variability HRV measures. Influencing this for general wellness is different from using any device to manage a cardiac condition, which should always involve a healthcare provider.

Can you improve HRV?

For many people, yes, HRV can be supported. Slow paced breathing and HRV biofeedback have meta-analytic evidence for reducing stress and supporting vagally mediated HRV, and research on non-invasive vagus nerve stimulation suggests it can raise HRV markers with regular use. Sleep, exercise, limiting alcohol, and managing stress all matter too. The most meaningful comparison is your own trend over weeks, not a single reading or someone else's number.

What is a good HRV?

There is no universal "good" number, because HRV is heavily shaped by age, sex, fitness, and genetics, and it declines with age. The most useful benchmark is your own baseline: a good HRV is one that is stable or trending upward for you and recovers well after stress or poor sleep. Population reference ranges exist for context, but flexibility, not a single value, is the real goal.

Do HRV breathing exercises actually work?

The research is encouraging for general wellness. A meta-analysis of randomized trials found breathwork reduced self-reported stress, and meta-analyses of HRV biofeedback found large reductions in stress and anxiety. These exercises engage the same parasympathetic pathway that governs heart rate, cost nothing, and have little downside for a healthy person, which makes them a sensible first thing to try.

Is non-invasive vagus nerve stimulation the same as the implanted kind?

No. Implanted vagus nerve stimulation involves surgery to place a device under the skin, and it is used in specific medical settings under a clinician's care. Non-invasive vagus nerve stimulation (nVNS) reaches the same nerve from outside the body, through the neck or ear, with no surgery. Consumer nVNS devices like Pulsetto are general wellness products, not surgical or prescription medical implants.

How long until I notice changes in HRV?

Effects vary by person and protocol, and the most consistent gains in the research tend to build with regular use over weeks rather than from a single session. A practical approach is to use the device or breathing practice daily, track HRV in an app, and look at the trend over four or more weeks rather than reacting to day-to-day swings, which are normal.

Scientific research

Pulsetto is a general wellness product and is not intended to diagnose, treat, cure, or prevent any disease or medical condition. The studies below were identified through the Consensus and PubMed databases, are linked directly by DOI, and are indexed in PubMed. They are provided for educational context on the vagus nerve, heart rate variability, breathing practices, and non-invasive vagus nerve stimulation, and do not constitute medical advice or a claim about any specific product.

[1] An Overview of Heart Rate Variability Metrics and Norms (Shaffer et al., 2017, Frontiers in Public Health. PMID: 29034226)

[2] Stress and Heart Rate Variability: A Meta-Analysis and Review of the Literature (Kim et al., 2018, Psychiatry Investigation. PMID: 29486547)

[3] Quantifying acute physiological biomarkers of transcutaneous cervical vagal nerve stimulation in the context of psychological stress (Gurel et al., 2019, Brain Stimulation. PMID: 31439323)

[4] Transcutaneous cervical vagal nerve stimulation reduces sympathetic responses to stress in posttraumatic stress disorder: A double-blind, randomized, sham-controlled trial (Gurel et al., 2020, Neurobiology of Stress. PMID: 33344717)

[5] Effect of breathwork on stress and mental health: A meta-analysis of randomised-controlled trials (Fincham et al., 2023, Scientific Reports. PMID: 36624160)

[6] Modulating Heart Rate Variability through Deep Breathing Exercises and Transcutaneous Auricular Vagus Nerve Stimulation (Jensen et al., 2022, Sensors. PMID: 36298234)

[7] Heart Rate Variability Biofeedback Improves Emotional and Physical Health and Performance: A Systematic Review and Meta Analysis (Lehrer et al., 2020, Applied Psychophysiology and Biofeedback. PMID: 32385728)

[8] The effect of heart rate variability biofeedback training on stress and anxiety: a meta-analysis (Goessl et al., 2017, Psychological Medicine. PMID: 28478782)

[9] The effect of transcutaneous auricular vagus nerve stimulation on HRV in healthy young people (Geng et al., 2022, PLoS ONE. PMID: 35143576)

[10] Ear your heart: transcutaneous auricular vagus nerve stimulation on heart rate variability in healthy young participants (Forte et al., 2022, PeerJ. PMID: 36438582)

[11] Transcutaneous auricular Vagus Nerve Stimulation and Median Nerve Stimulation reduce acute stress in young healthy adults (Sanchez-Perez et al., 2023, Frontiers in Neuroscience. PMID: 37746156)

[12] Does transcutaneous auricular vagus nerve stimulation affect vagally mediated heart rate variability? A living and interactive Bayesian meta-analysis (Wolf et al., 2021, Psychophysiology. PMID: 34473846)

[13] A systematic review of the effects of transcutaneous auricular vagus nerve stimulation on baroreflex sensitivity and heart rate variability in healthy subjects (Soltani et al., 2023, Clinical Autonomic Research. PMID: 37119426)

[14] Age as an Effect Modifier of the Effects of taVNS on Heart Rate Variability in Healthy Subjects (Gianlorenco et al., 2024, Journal of Clinical Medicine. PMID: 39064307)

[15] Critical Review of Transcutaneous Vagus Nerve Stimulation: Challenges for Translation to Clinical Practice (Yap et al., 2020, Frontiers in Neuroscience. PMID: 32410932)

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